Wednesday, October 3, 2012

Classification of Penicillin with source and function

Classification of Penicillin According to the source : A)     Natural penicillin Oral: (1) Phenoxy-methyl-penicillin ( Penicillin- v), (2) Phenethicillin penicillin Parenteral : Benzyl penicillin ( Penicillin-G ). B)      Semisynthetic  penicillin (β-lactamase resistance) 1)      Narrow spectrum penicillin ( penicillinase resistance ): Oxacillin ,Cloxacillin,...

What is penicillin and Source of Penicillin

PENICILLINS It is the oldest member of bactericidal antibiotics . Sir Alexander  Fleming discovered penicillin in 1928. In 1940 Chain , Folery and their  associates first produce significant quantities  of penicillin from cultures of Penicillium  notatum .  Penicillins are lipid insoluble.  penicillin Cannot cross the blood brain barrier. Can cross the placental barrier. Source of Penicillin : 1. Natural...