What is Protein & its properties , functions

Protein Protein is complex organic nitrogenous compound composed of amino acids linked together by peptide bonds. Sources : Meats , Fish , Milk , Egg, Vegetables etc. protien foods Properties of protein : ·         Protein are colloidal in nature. ·         They are generally soluble in water , weak  salt solution, dilute acids and alkalies. ·         Protein...

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Mechanism of action of Penicillin

Mechanism of action of Penicillin             Penicillin first binds with specific penicillin binding proteins (PBPs) that serves as drug receptor on bacteria. Then – Ø  Penicillin acts as a selective inhibitor of transpeptidase enzyme . So the transpeptidation (cross-linking) reaction is inhibited and peptidoglycine synthesis is blocked. As a result a fragile cell membrane is formed and thus cell membrane...

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General structure of penicillin

                   Structure of Penicillin                 Penicillin consists of a Thiazolidine ring (α) attached to a β – lactam ring .  The rings constitute the fundamental nucleus of all the penicillin called 6-amino-penicillanic acid (6-APA).  β- lactam ring carries a free amino group to which acid radical can be attached to synthesis a...

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Indication of Penicillin

Indication of Penicillin A)    Pneumococcal  infection : ·        Pneumococcal pneumonia ·        Pneumococcal empyema ·        Pneumococcal meningitis ·        Other pneumococcal infections Suppurative arthritis , Osteomyelitis , Acute suppurative mastoiditis , Peritonitis. B)   ...

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