What is Protein & its properties , functions

Protein Protein is complex organic nitrogenous compound composed of amino acids linked together by peptide bonds. Sources : Meats , Fish , Milk , Egg, Vegetables etc. protien foods Properties of protein : ·         Protein are colloidal in nature. ·         They are generally soluble in water , weak  salt solution, dilute acids and alkalies. ·         Protein...

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Mechanism of action of Penicillin

Mechanism of action of Penicillin             Penicillin first binds with specific penicillin binding proteins (PBPs) that serves as drug receptor on bacteria. Then – Ø  Penicillin acts as a selective inhibitor of transpeptidase enzyme . So the transpeptidation (cross-linking) reaction is inhibited and peptidoglycine synthesis is blocked. As a result a fragile cell membrane is formed and thus cell membrane...

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General structure of penicillin

                   Structure of Penicillin                 Penicillin consists of a Thiazolidine ring (α) attached to a β – lactam ring .  The rings constitute the fundamental nucleus of all the penicillin called 6-amino-penicillanic acid (6-APA).  β- lactam ring carries a free amino group to which acid radical can be attached to synthesis a...

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Indication of Penicillin

Indication of Penicillin A)    Pneumococcal  infection : ·        Pneumococcal pneumonia ·        Pneumococcal empyema ·        Pneumococcal meningitis ·        Other pneumococcal infections Suppurative arthritis , Osteomyelitis , Acute suppurative mastoiditis , Peritonitis. B)   ...

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Pharmaceutical Aids and Technical Products

Pharmaceutical Aids and Technical Products     A number of natural products find use in various fields in addition to medicine and pharmacy. These products are called technical products which are used in beverages, condiments, flavoring agent spices , paints ,varnishes and cosmetics. pharmaceutical aids Pharmaceutical aids  For the production of drug various techniques like as purification, filtration, adsorption, solubilization,...

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Classification of Penicillin with source and function

Classification of Penicillin According to the source : A)     Natural penicillin Oral: (1) Phenoxy-methyl-penicillin ( Penicillin- v), (2) Phenethicillin penicillin Parenteral : Benzyl penicillin ( Penicillin-G ). B)      Semisynthetic  penicillin (β-lactamase resistance) 1)      Narrow spectrum penicillin ( penicillinase resistance ): Oxacillin ,Cloxacillin,...

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What is penicillin and Source of Penicillin

PENICILLINS It is the oldest member of bactericidal antibiotics . Sir Alexander  Fleming discovered penicillin in 1928. In 1940 Chain , Folery and their  associates first produce significant quantities  of penicillin from cultures of Penicillium  notatum .  Penicillins are lipid insoluble.  penicillin Cannot cross the blood brain barrier. Can cross the placental barrier. Source of Penicillin : 1. Natural...

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